Confluent reticulated papillomatosis - 汇合性网状乳头状瘤病https://en.wikipedia.org/wiki/Confluent_and_reticulated_papillomatosis
汇合性网状乳头状瘤病 (Confluent reticulated papillomatosis) 是一种罕见但独特的获得性鱼鳞病样皮肤病,其特征是持续性深色鳞状斑块,往往主要位于中央躯干。该病可用米诺环素治疗。

治疗
#Minocycline
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  • 典型病例 ― 腰部周围出现黑色素斑,无任何症状(瘙痒、疼痛)。
  • 严重形式
  • 腰部是一个常见的位置。
References Confluent and Reticulated Papillomatosis 29083642 
NIH
Confluent and reticulated papillomatosis (CRP) ,也称为 Gougerot-Carteaud 综合征,由皮肤细胞异常生长引起。它表现为无痛的黑斑,可以合并成更大的斑块,通常出现在青少年和年轻人的上胸部和颈部。最初的治疗选择是米诺环素。
Confluent and reticulated papillomatosis (CRP), also known as Gougerot-Carteaud syndrome, is caused by disordered keratinization. It presents with asymptomatic hyperpigmented papules that can coalesce into plaques and are typically located on the upper trunk and neck of teens and young adults. First-line treatment is oral 'minocycline'.
 Confluent and reticulated papillomatosis: diagnostic and treatment challenges 27601929 
NIH
CRP 通常在颈部、腋窝、上胸部和上背部皮肤上表现为黑斑和斑块,但没有任何症状。有时,它可以向上扩散到前额,向下扩散到耻骨区域。像 minocycline 这样的抗生素已经成为首选的治疗选择。
CRP typically presents as asymptomatic hyperpigmented papules and plaques with peripheral reticulation over the nape, axillae, upper chest, and upper back, occasionally with extension superior to the forehead and inferior to the pubic region. Antibiotics, such as 'minocycline', at anti-inflammatory doses have emerged as a preferred therapeutic option.