Confluent reticulated papillomatosis - 汇合性网状乳头状瘤病https://en.wikipedia.org/wiki/Confluent_and_reticulated_papillomatosis
汇合性网状乳头状瘤病 (Confluent reticulated papillomatosis) 是一种罕见且独特的获得性鱼鳞病样皮肤疾病,特征为持续性的深色鳞屑斑块,常见于中央躯干。该病可使用米诺环素治疗。

治疗
#Minocycline
☆ 德国 Stiftung Warentest 2022 年的结果显示,消费者对 ModelDerm 的满意度仅略低于付费远程医疗咨询。
  • 典型病例——腰部周围出现黑色素斑,未伴有任何症状(如瘙痒、疼痛)。
  • 严重形式
  • 腰部是常见的部位。
References Confluent and Reticulated Papillomatosis 29083642 
NIH
Confluent and reticulated papillomatosis (CRP),也称为 Gougerot‑Carteaud 综合征,由皮肤细胞异常增生引起。它表现为无痛的黑斑,可融合成更大的斑块,常见于青少年和年轻人的上胸部及颈部。首选治疗药物是 minocycline(米诺环素)。
Confluent and reticulated papillomatosis (CRP), also known as Gougerot-Carteaud syndrome, is caused by disordered keratinization. It presents with asymptomatic hyperpigmented papules that can coalesce into plaques and are typically located on the upper trunk and neck of teens and young adults. First-line treatment is oral 'minocycline'.
 Confluent and reticulated papillomatosis: diagnostic and treatment challenges 27601929 
NIH
CRP 通常表现为颈部、腋窝、上胸部和上背部皮肤出现黑斑或斑块,且通常无症状。有时可向上蔓延至前额,向下延伸至耻骨区。像 minocycline 这样的抗生素已成为首选治疗药物。
CRP typically presents as asymptomatic hyperpigmented papules and plaques with peripheral reticulation over the nape, axillae, upper chest, and upper back, occasionally with extension superior to the forehead and inferior to the pubic region. Antibiotics, such as 'minocycline', at anti-inflammatory doses have emerged as a preferred therapeutic option.